Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling
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چکیده
منابع مشابه
Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling.
Syndecan-4 is a ubiquitous transmembrane proteoglycan that localizes to the focal adhesions of adherent cells and binds to a range of extracellular ligands, including growth factors and extracellular-matrix proteins. Engagement of syndecan-4 is essential for adhesion formation in cells adhering via certain integrins, and for cell proliferation and migration in response to growth factors. The cy...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2002
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20021228